王彦林，博士，主任医师，博士生导师，中国福利会国际和平妇幼保健院产前诊断中心&胎儿医学科学科带头人，擅长：遗传性疾病的产前诊断及遗传咨询、胎儿发育异常、高危妊娠及复杂性双胎全程管理及诊治。承担在研国家级、省部级课题多项，近年在NEJM，Clin Chem，AJOG，JMD等国内外期刊发表多篇论文。多个专业学术团体任职：中国优生优育协会胎儿医学专委会副主任委员，上海市医师协会罕见病专委会副会长，上海市医学会医学遗传学组副主任委员，上海市产前诊断技术质控中心秘书长，上海市出生缺陷预防保健中心秘书长，上海市医师协会母胎医学分会秘书，上海医学会妇产科学组围产分会委员。
主要科研项目
1. 科技部重点研发计划，2023YFC2705901，双胎妊娠严重母胎并发症高危因素筛选和多模态AI预测方案研究，项目负责人。 2. 上海市卫健委一区一特科普项目，23DZ2300300，妇幼健康，奉贤无限，项目负责人。 3. 国家自然科学基金面上项目，81971401，线粒体基因组变异在特发性胎儿生长受限中的作用及机制研究：基于MCDA双胎，项目负责人。 4. 上海市科学技术委员会上海市科研计划项目，22Y11902300，基于三代测序的SMA一体化检测技术研发及临床应用，项目负责人。 5. 上海交通大学医工交叉重点项目，YG2023ZD26，出生缺陷产前诊断中临床意义未明拷贝数变异3D基因组异常结构智能分析与临床应用，项目负责人。 6. 上海市科学技术委员会上海市科研计划项目，18140902500，同种异体及人源化兔嵌合胎盘动物模型的构建，项目负责人。 7. 上海市科学技术委员会上海市科研计划项目，16411962800，靶向性无创产前筛查在双胎妊娠检测的临床价值，项目负责人。 8. 上海市卫生和计划生育委员会项目，201540377，胎盘mtDNA突变及拷贝数异常与sIUGR相关性研究，项目负责人。 代表性论文（#第一作者，*通讯作者）
1. Wang Y, Guo Z, Ye B, Liu L, Mao X, Luo Y, Gao S, He G, Bian S. Association of SARS-CoV-2 Infection during Early Weeks of Gestation with Situs Inversus. N Engl J Med. 2023 Nov 2;389(18):1722-1724. 2. Li S, Han X, Zhang L, Xu Y, Chang C, Gao L, Zhan J, Hua R, Mao A, Wang Y#. An Effective and Universal Long-Read Sequencing-Based Approach for SMN1 2 + 0 Carrier Screening through Family Trio Analysis. Clin Chem. 2023 Nov 2;69(11):1295-1306. 3. Zhu J, Zhang J, Wu Y, Gao L, Zhao X, Cheng W, Wang Y. Intertwin growth discordance throughout gestation and hypertensive disorders of pregnancy. Am J Obstet Gynecol. 2023 Jun;228(6):730. 4. Li S, Shi Y, Han X, Chen Y, Shen Y, Hu W, Zhao X, Wang YL#. Prenatal Diagnosis of Chromosomal Mosaicism in Over 18,000 Pregnancies: A Five-Year Single-Tertiary-Center Retrospective Analysis. Frontiers in genetics 2022, 13:876887. 5. Li S, Han X, Xu Y, Chang C, Gao L, Li J, Lu Y, Mao A, Wang YL#. Comprehensive Analysis of Spinal Muscular Atrophy: SMN1 Copy Number, Intragenic Mutation, and 2 + 0 Carrier Analysis by Third-Generation Sequencing. The Journal of molecular diagnostics : JMD 2022. 6. Gao L, Xu QQ, Wang S, Xia YQ, Zhao XR, Wu Y, Hua RY, Sun JL, Wang YL#. Correlation analysis of adverse outcomes for the selective reduction of twin pregnancies. BMC pregnancy and childbirth 2022, 22(1):417. 7. Long Z, Huang L, Lyu J, Xia Y, Chen Y, Li R, Wang Y#, Li S#. Trends of central obesity and associations with nutrients intake and daily behaviors among women of childbearing age in China. BMC women's health 2022, 22(1):12. 8. Long Z, Huang L, Lyu J, Xia Y, Chen Y, Li R, Wang Y#, Li S#. The associations of perceived stress with food preferences and activity preferences: a cross-sectional study among Chinese adults. Journal of affective disorders 2022, 297:430-436. 9. Xia YQ, Lyu SP, Zhang J, Chen YT, Gao L, Zhao AD, Wang YL#, Li SH#. Development of fetal growth charts in twins stratified by chorionicity and mode of conception: a retrospective cohort study in China. Chinese medical journal 2021, 134(15):1819-1827. 10. Zhao, Xin-Rong; Gao, Li; Sun, Jin-Ling; Hua, Ren-Yi; Wu, Yi; Wang YL#. Clinical significance of nuchal translucency measurement in routine prenatal examination, Chinese Medical Journal: June 24, 2021 - Volume Publish Ahead of Print 11. Lyu S, Gao L, Sun J, Zhao X, Wu Y, Hua R, Wang Y#. The association between maternal complications and small for gestational age in twin pregnancies using singleton and twin birth weight references. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstet 2021:1-7. 12. Huang L, Long Z, Lyu J, Chen Y, Li R, Wang Y#, Li S#. The Associations of Trajectory of Sleep Duration and Inflammation with Hypertension: A Longitudinal Study in China. Nature and science of sleep 2021, 13:1797-1806. 13. Gao, Li; Lyu, Shu-Ping; Zhao, Xin-Rong; Wu, Yi; Hua, Ren-Yi; Wang, Shan; Zhang, Yan; Wang, Yan-Lin#. Systematic management of twin pregnancies to reduce pregnancy complications, Chinese Medical Journal: June 5, 2020 - Volume 133 - Issue 11 - p 1355-1357. 14. Zhao, Xin-Rong, Gao, Li, Wu, Yi, & Wang YL#. Application of chromosomal microarray in fetuses with increased nuchal translucency. The Journal of Maternal-Fetal & Neonatal Medicine, 2020, 33(10), 1749-1754. 15. Sun L, Wang YL#. Demographic and perinatal outcome data of fetuses with SUA/PRUV. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstet 2018, 31(9):1118-1123. 16. Wu WB, Xu YY, Cheng WW, Wang YL#, Zhang HJ. Decreased PGF may contribute to trophoblast dysfunction in fetal growth restriction. Reproduction. 2017 Sep;154(3):219-229. 代表性著作： 1. 《产前遗传咨询手册》，上海交通大学出版社，副主编，2023年12月 2. 《临床检验一万个为什么——遗传检验分册》，人民卫生出版社，副主编，即将出版
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