基本信息

姓名:

范建霞

职称:

主任医师

导师类型:

博士生导师,研究员

专业:

妇产科学

研究方向:

妊娠期内分泌疾病的临床及基础研究

邮箱地址:

fanjianxia122@126.com

个人简介

  

范建霞,上海交通大学医学院附属国际和平妇幼保健院主任医师、研究员、博士生导师。国家重点研发计划项目首席科学家,国家自然科学基金-国际重大合作项目中方首席,可支配经费三千余万。从事妇产科临床和科研工作40年,关注妊娠期内分泌与代谢性疾病的临床及基础研究,在Thyroid, JCEM等国际著名杂志发表SCI论文80余篇。获华夏医学科技奖三等奖,上海医学科技奖三等奖,上海市优秀专科医师提名奖等多项科技奖励及荣誉称号。

 

主要科研项目:

1. 国家自然科学基金委员会与加拿大卫生研究院健康生命轨迹计划(HeLT1)队列合作课题:预防儿童肥胖的社区-家庭-母婴综合干预队列研究,82111015,中方首席

2. 科技部国家重点研发计划:自发性早产的动因学研究“分娩启动和早产机理与干预”,2018YFC1004602,项目负责人

3. 上海市卫健委,第四轮公共卫生三年行动计划重点学科项目-二胎政策下高危孕产妇的管理,15GWZK0701,项目负责人

4. 国家自然科学基金面上项目,胎盘源性外泌体miR-577调控FGF21在妊娠期糖尿病中的作用机制研究,81974235,项目负责人

5. 国家自然科学基金面上项目,miR221/222在妊娠期糖尿病致子代影响中作用机制的研究,81471516,项目负责人

6. 申康新兴前沿技术联合攻关项目,妊娠期低甲状腺素血症不良妊娠结局风险评估模型的优化与临床干预研究,SHDC12022119,项目负责人

 

代表性论文(#第一作者,*通讯作者)

1. Xi Yang, Yamei Yu, Chen Zhang, Yong Zhang, Zhirou Chen, Lise Dubois, He-Feng Huang, William D. Fraser, Jianxia Fan. The Association Between Isolated Maternal Hypothyroxinemia in Early Pregnancy and Preterm Birth. Thyroid, 2020, 30 (12): 1724-1731.

2. Yindi Liu, Fei Guo, Maraka Spyridoula, Yong Zhang, Chen Zhang, Tim I. M. Korevaar, Jianxia Fan. Associations between Human Chorionic Gonadotropin, Maternal Free Thyroxine, and Gestational Diabetes Mellitus. Thyroid, 2021, 31 (8): 1282-1288.

3. Zhirou Chen, Xi Yang, Chen Zhang, Zheng Ding, Yong Zhang, Tim I. M. Korevaar, Jianxia Fan. Thyroid Function Test Abnormalities in Twin Pregnancies. Thyroid, 2021, 31 (4): 572-579.

4. Shuai Yang, Feng-Tao Shi, Peter C. K. Leung, He-Feng Huang, Jianxia Fan. Low Thyroid Hormone in Early Pregnancy Is Associated with an Increased Risk of Gestational Diabetes Mellitus. The Journal of Clinical Endocrinology and Metabolism, 2016, 101 (11): 4237-4243.

5. Jianxia Fan, Yong Zhang, Chen Zhang, Mirjana Barjaktarovic, Xi Yang, Robin P. Peeters, He-Feng Huang, Tim Korevaar. Persistency of Thyroid Dysfunction From Early To Late Pregnancy. Thyroid, 2019; 29 (10): 1475-1484.

6. Wu W, Zhou Y, Liu Y, Liu C, Ren J, Liu X, Korevaar TIM, Fan J. Triglycerides Mediate the Relationship Between Maternal Free Thyroxine and Birth Weight: A Prospective Cohort Study from China. Thyroid. 2023; 33(5): 615-624.

7. Yang X, Zhou Y, Li H, Song F, Li J, Zhang Y, Lin Y, Zhang H*, Fan J, Wu W.  Autophagic flux inhibition, apoptosis, and mitochondrial dysfunction in bile acids-induced impairment of human placental trophoblast. Journal of Cellular Physiology. 2022; 237(7): 3080-3094.

8. Xi Yang, Chen Zhang, Catherine Williamson, Yindi Liu, Yulai Zhou, Chunxiao Liu, Lei Chen, Yong Zhang, Tim Korevaar, Weibin Wu, Jianxia Fan. Association of maternal thyroid function with gestational hypercholanemia. Thyroid, 2022; 32(1): 97-104.

9. Yong Zhang, Chen Zhang, Xi Yang, Shuai Yang, Yu Meng, Zhiwei Liu, Robin P. Peeters, He-Feng Huang, Tim I. M. Korevaar, Jianxia Fan. Association of maternal thyroid function and thyroidal response to human chorionic gonadotropin with early fetal growth. Thyroid, 2019, 29 (4): 586-594.

10. Chen Zhang, Xi Yang, Yong Zhang, Fei Guo, Shuai Yang, Robin P. Peeters, Tim Korevaar, Jianxia Fan, Huang HF. Association Between Maternal Thyroid Hormones and Birth Weight at Early and Late Pregnancy. The Journal of Clinical Endocrinology and Metabolism, 2019; 104 (12): 5853-5863.

 

代表性著作

1. 《宫内儿科学》,专著,2023/11,人民卫生出版社,参编

2. 《中华妇产科学》,专著,2023/07,人民卫生出版社,参编

3. 《发育源性疾病》,专著,2022/09,人民卫生出版社,参编

4. 《难产》,专著,2021/07,人民卫生出版社,参编

 

 

 

 

 

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